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However, cancer cells have developed various mechanisms for T cell depletion, which is an adverse factor in HCC, circumventing immune monitoring, such as promoting T cell fatigue blocking T cell penetration, and inducing immunosuppressive factors [86]

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C.IngoldI.et al (2019)

The trial aimed to examine the drugs effects on biomarker, volumetric magnetic resonance imaging (MRI) findings, and clinical outcomes [77]